The Sanctuary is a religious building located directly north of Inoa Village. It is heavily modelled after High to Late Middle Ages Catholic abbeys, carrying the same air and purpose; with a hospital ward, kitchen, graveyard, crypt, library, school and other rooms. It can be revisited after completion, but in the closing stages of the end of the game becomes locked.
Alundra and Septimus agree to enter the Sanctuary to ascertain Ronan's true motives the day after visiting Magyscar. After breaking and entering, the duo find many traps and hidden rooms, until the shrine beneath the altar is revealed. Ronan himself stands before them and explains that not only do the villagers know of the shrine, but they have worshipped within before.
Later, after the fire of Inoa, Alundra returns for a final confrontation with Ronan, where the priest calls upon the powers of Melzas to transform him into a twisted demon. After Ronan's death, the villagers take refuge in the shrine, having destroyed the statue of Melzas. It is after these events that the Sanctuary is locked, and can no longer be revisited.
While most dungeons in the game have exactly one each of Gilded Falcon and Life Vessel, the Sanctuary lacks a Gilded Falcon. This makes it one of a handful of exceptions, the others being Wendell's Dream, Olen's Nightmare, the Fairy Pond, and the Tower of the Great Tree.
|Alundra – Meia|
|Beaumont – Bergus – Bonaire – Elene – Fein – Giles – Gustav – Jess – Kisha – Kline – Lutas – Meade – Myra|
Nadia – Naomi – Nestus – Phineas – Rumi – Septimus – Sierra – Sybill – Talis – Thyea – Wendell – Yuri – Yustel
|Berue – Cephas – Jaylen – Jeal – Keysmith – King Miming – King Snow – Kōhei – Lars – Lurvy – Lyman|
Melzas – Merrick – Nava – Nirude – Olen – Ronan – Stenia – Uma – Vul – Wilda – Zane – Zazan – Zorgia
|The Klark – Inoa Village – Tarn's Manor – Coal Mine – Lars' Crypt – Despair Desert – Ancient Shrine|
Coastal Cave – Reptile Lair – Magyscar – Sanctuary – Underground Waterway – Nirude's Lair
Fairy Pond – Murgg Woods – Tower of the Great Tree – Torla Mountain – Nava's Keep – Lake Shrine
|Crest – Dreamwalker – Gilded Falcon – Gazeck – Guardians of the Seal|
Life Vessel – Magic Seed – Murgg – Teleport Arch – Zolist
|Enemies – Equipment – Items|
|Tarn's Manor – Wendell's Dream – Olen's Nightmare – Coal Mine – Lars' Crypt – Bonaire's Dream|
Ancient Shrine – Coastal Cave – Kline's Nightmare – Reptile Lair – Giles' Dream – Magyscar – Sanctuary
Meia's dream – Underground Waterway – Nirude's Lair – Fairy Pond – Elene's Dream – Murgg Woods
Tower of the Great Tree – Torla Mountain – Nestus' Nightmare – Nava's Keep – Lake Shrine
|Airship – Kindra Forest – Mt. Sparrowhawk – Tortuga Beach – Ox Tank – Howling Cave – Dun Webb|
Gold Badge Testing Center – Beneath Milena's Mansion – Underwater Cave – Sunk Ship – Siren Ruins
Eden Ruins – Paco Ruins – Demon Whale – Varuna Dungeons – Church of the Key – Turnkey Dam
Mount Firedrake – Underwater Passage – Dark Isle – Dragonia – Old Varuna Ruins – Star Key